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Precipitation of opioid withdrawal syndrome When initiating treatment with Subutex, it can be crucial to be familiar with the partial agonist profile of buprenorphine. Sublingually administered buprenorphine can precipitate withdrawal indications in opioid-dependent patients if administered ahead of the agonist results resulting from recent opioid use or misuse have subsided.

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Go ahead and take medication when you may, but skip the skipped dose if it is nearly time on your upcoming dose. Will not acquire two doses at just one time.

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Abuse of Subutex may cause a person to generally be impulsive, just take better risks, and make weak selections, which can result in amplified costs of accidents, accidents, or the opportunity for contracting a sexually transmitted or infectious ailment.

• For clients receiving methadone: in advance of beginning Subutex therapy, the dose of methadone really should be lowered to the highest of 30mg/working day. Subutex could precipitate indications of withdrawal in sufferers depending on methadone.

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4.7 Effects on ability to drive and use equipment Buprenorphine has average impact on the opportunity to use devices when administered to opioid dependent sufferers. Subutex may possibly bring about drowsiness, dizziness or impaired imagining, In particular all through procedure induction and dose adjustment.
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